Principal Scientist, Medicinal Chemistry

San Diego, Boston, Full Time

Rapport Therapeutics, a well-funded start-up with labs in San Diego is recruiting a self-motivated Chemist to help discover small molecule precision neuroscience therapeutics. The ideal candidate has medicinal chemistry experience with CNS target, thrives on rigorous experimentation, and is a team player. The candidate will be an integral member of a diverse drug discovery team, with ample opportunity for career development.

  • Responsible for design and external synthesis of compounds that lead to the identification clinical development candidates
  • Manage external chemists and collaborations to deliver on aggressive timelines
  • Network across the multifunctional research team and integrate data across biology, ADME, toxicology and other domains, to drive medicinal chemistry strategies
  • Actively follow scientific and biopharma literature within the areas of research interest

Requirements and Qualifications:

  • PhD in organic chemistry and 5 +years of relevant pharmaceutical industry experience
  • Exemplary skills in organic and medicinal chemistry techniques including parallel library design and synthesis, structure-based design, analytical methods, and purification methods
  • Strong organizational, managerial and communication skills
  • Experience in functioning within a matrix driven organization required
  • Strong leadership skills and a track record of success in all aspects of medicinal chemistry and drug discovery: hit identification, hit to lead and lead optimization
  • Demonstrated record of delivering clinical candidates
  • Experience in managing external chemistry FTE resources is a plus
Job Type: Full Time
Job Location: West Coast East Coast
Job City: San Diego Boston

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